I can't claim detailed knowledge of his career, but he did produce one of my favourite albums, Bob Dylan's masterpiece of bad-tempered spirituality Slow Train Coming, the first record of his born-again Christian era.
The most famous story from the Wexler/Dylan encounter is told as follows:
During the recording Dylan tried to interest Wexler in Biblical matters. Wexler comments: "When I told him he was dealing with a confirmed 63-year-old Jewish atheist, he cracked up." Wexler was tolerantly amused by the whole business: "I liked the idea of Bob coming to me, the Wandering Jew, to get the Jesus feel."
But I see that like all famous anecdotes, its factual accuracy is challenged - see here.
Whatever the truth, their liaison resulted in a great record.